These are very capable EMS's and will run a 1UZ just fine with fully sequential injection and a wasted spark ignition. Obviously it'll run a UZ with distributors too, but who would want to with a standalone?
I've had one running a boosted 1UZ on an engine dyno up to 23-25 psi, and I've had one in my singled Supra for many years.
It has tons of I/O which can be used for boost control, methanol injection, secondary injection, NOS, transmission control, etc. To give an idea of its capability, it has three 40 pin electrical connectors, so 120 pins total.
It will also run either a GM or Toyota/Lexus stepper type IAC, which many standalones have trouble doing, and it has a completely separate idle fuel map, which many of the latest ECU's still don't have.
Programming is not for beginners, however. A good, professional tuner who already knows the product is strongly recommended to set it up correctly. Even a pro tuner who is excellent on other EMS's will be challenged to set one of these up correctly the first time.
If someone wants a bargain on an older, but still very capable EMS, this is a great deal.